Şişli, Istanbul
Aesthetic Treatments

PB Serum

A Spanish enzyme-based serum containing collagenase, lipase, and hyaluronidase, used in aesthetic and enzyme therapies.

PB Serum

What Is PB Serum and How Is It Performed?

PB Serum

PB Serum is a product of Spanish origin. It is manufactured for aesthetic purposes in Proteos Biotech laboratories. It is also effective in treating a number of conditions when combined with enzyme therapy. PB Serum contains 3 enzymes, namely collagenase, lipase and hyaluronidase.

PB Serum Types

PB Serum comes in 3 types. Let's take a closer look at the PB Serum types, listed as low, medium and high.

Low PB Serum

The area where the Low type of PB Serum is most commonly used is under the eyes. It is a product used to eliminate under-eye bags, tighten excess under-eye skin, and regenerate the skin. Low PB Serum is preferred for under-eye rejuvenation and tightening. Sometimes a single session is sufficient, but depending on the patient's under-eye condition, 2 sessions may be needed. It is also an effective procedure for hand rejuvenation.

Medium PB Serum

It is used to break down fat tissue in the treated area. Medium PB Serum is known as a fat-burning, fat-dissolving product. It is most commonly used on the jowl (under the chin) area, the inner thighs, the arms, the knees, the calves and the abdomen to melt fat. Medium PB Serum not only burns the fat in the area where it is applied, but also tightens and lifts any sagging that may occur or already exist. The duration of treatment varies from person to person and according to the area being treated. If additional improvement is needed, several sessions of PB Serum treatment can be performed.

High PB Serum

High PB Serum contains the collagenase enzyme. With High PB Serum, postoperative scars, scars, burn scars, keloids, stretch marks, body sagging, deep wrinkles, cellulite and resistant fibrosis can be treated. The collagenase enzyme treats the areas where High PB Serum is applied. It heals the tissue by breaking down existing scar tissue in these areas and supporting the formation of new, healthy tissue. It shows its effect within 1-4 sessions, depending on the patient's condition and the needs of the area being treated.

PB Serum Side Effects

The application has no known side effects. PB Serum is not used on people under the age of 18. Unfortunately, no type of PB Serum can be used if you are not over 18 years old.
  • Slight redness of the skin on the day of application,
  • Itchy skin,
  • Mild edema,
  • Sensitivity in the applied area.

Things to Consider After PB Serum Application

  • Regardless of which type of PB Serum is applied to your body, you should rest and drink water on the day of treatment.
  • We recommend that you refrain from Turkish baths, saunas, swimming and sports on the day of the PB Serum application.
  • These recommendations only apply on the day of the procedure, and you can go about your routine as usual on the following days.
  • Drink plenty of water for 2 days.

How PB Serum Differs from Other Applications

What sets PB Serum apart from other applications is that its effect lasts longer. Because PB Serum has a therapeutic quality, it repairs the impaired mechanism in the body and enables it to become active again. Other similar products only temporarily heal the damaged area. Compared to other products, PB Serum contains enzymes with three different properties and produces a more positive effect. Since it comes in different types, it can be used on different parts of the body and for different problems. It can safely be reapplied once its effect wears off after the treatment is complete.

How Is PB SERUM Applied?

  • First, before photos are taken.
  • The skin is numbed with a cream.
  • The skin is then disinfected.
  • The injection, which comes in a special form, is applied by marking out or dividing the areas to be treated.
  • The procedure takes 15-20 minutes.
  • It does not affect daily life.

What Is the PB Serum Price?

Centers approved by the Ministry of Health are not permitted to state prices on their websites. For this reason, you can get information about "PB Serum" prices by calling our clinic at 0(212) 225 08 00.
Pricing Information 2026

PB Serum Prices 2026

PB Serum prices can vary depending on several factors, including the type of product or device used, the size of the treatment area, the experience of the physician performing the procedure, and the clinic's location. For detailed pricing and to book an appointment, you can reach us at +90 (532) 324 94 54.

When Is PB Serum Recommended?

PB Serum is one of the most effective and safe dermatological solutions offered by modern medicine, providing a targeted intervention for correcting skin deformations, signs of aging, or clinical concerns.

Correcting volume loss and asymmetry in facial contours
Softening fine lines and deep wrinkles
Improving skin elasticity and boosting collagen production
Restoring vibrancy to tired, dull, and lackluster skin
Achieving a more youthful, lifted facial appearance in line with the golden ratio

How Is PB Serum Performed, Step by Step?

PB Serum is carried out at our clinic following a sterile, comfortable protocol tailored to each patient:

1Detailed Consultation and Skin Analysis: Our expert physicians assess your skin's needs and your expectations.
2Preparation and Sterilization: The treatment area is cleansed with antiseptic solutions, and an anesthetic cream is applied for local comfort.
3Precise Needle / Device Application: The relevant dermatological product or technology is delivered with precision to the anatomically correct depth.
4Soothing Aftercare and Review: The process concludes with a soothing cream and sunscreen applied to the treated area.

Aftercare Notes

  • Avoid getting the treated area wet or rubbing it for the first 24 hours.
  • Do not apply makeup to the injection sites or treatment area.
  • Avoid saunas, steam rooms, tanning beds, and intense sun exposure for the first 3 days.
  • Drink plenty of water and avoid using any skincare products other than those recommended by your doctor.

Who Is a Suitable Candidate?

  • Suitable Candidates: Patients over 18 in good general health with realistic expectations.
  • Not Recommended For: Pregnancy and breastfeeding, areas with active skin infection, uncontrolled autoimmune conditions, and known allergies to the relevant ingredients.

Expert Physician Opinion

Our Expert Dermatology Team

"Our expert dermatology team emphasizes that the goal of PB Serum is to achieve results that avoid an artificial look and instead work in harmony with the skin's natural texture while supporting facial anatomy. At our clinic, every treatment is individually dosed and planned according to each patient's unique skin structure."

Frequently Asked Questions (15 FAQs)

15 Most Common Questions & Answers About PB Serum

The 15 most searched questions on Google, answered by our expert dermatologists.

1PB Serum Prices 2026↓
PB Serum prices can vary depending on several factors, including the type of product used, the size of the treatment area, the experience of the physician performing the procedure, and the clinic's location. For detailed pricing and to book an appointment, you can reach us at +90 (532) 324 94 54.
2What Is PB Serum and How Does It Work?↓
PB Serum is a modern dermatological and aesthetic approach in the Aesthetic Treatments category that supports your skin's structure at a cellular level. Performed under clinical conditions, this treatment triggers tissue renewal, addresses the targeted concern, and delivers a healthier overall appearance.
3Who Is a Suitable Candidate for PB Serum?↓
PB Serum is suitable for all patients aged 18 and over who are in good general health and who want to achieve a fresher, more youthful and balanced facial appearance.
4How Long Do the Results of PB Serum Last?↓
The results of PB Serum can vary depending on individual metabolism, skin type, and lifestyle habits. On average, patients can expect the effects to last between 6 and 18 months, with the results maintained significantly longer through regular maintenance sessions.
5Is PB Serum Painful? Is Anesthesia Used?↓
Patient comfort is a top priority during PB Serum. Before the procedure, a high-strength local anesthetic cream is applied to numb the treatment area, ensuring maximum comfort throughout the session.
6What Should Be Considered Before PB Serum?↓
Before PB Serum, it is recommended — under your doctor's supervision — to pause blood thinners, alcohol consumption, and supplements such as vitamin E for at least 3-5 days. The treatment area should also be clean and free of makeup on the day of the procedure.
7What Is the Aftercare and Recovery Process Like Following PB Serum?↓
Most of our patients can return to their daily and social routines the same day after PB Serum. In the first 24 hours after the procedure, strenuous exercise, hot baths, saunas, and direct sun exposure should be avoided.
8When Do the Effects of PB Serum Become Visible?↓
The first effects of PB Serum become noticeable shortly after the procedure. The tissue fully settles, any swelling resolves, and the final results typically emerge within 1 to 2 weeks.
9Are There Any Side Effects or Risks Associated with PB Serum?↓
PB Serum is extremely safe when performed by an experienced dermatologist under sterile clinical conditions. Mild redness, minor swelling, or bruising may occur at the injection or treatment site, and these typically resolve on their own within 2-4 days.
10How Many Sessions of PB Serum Are Required?↓
The number of sessions required for PB Serum is determined by our expert physicians based on the patient's needs and tissue condition. While some treatments deliver excellent results in a single session, others may require a course of 2-4 sessions.
11Can PB Serum Be Combined with Other Aesthetic or Skin Treatments?↓
Yes, PB Serum can be combined with other medical aesthetic and dermatological treatments such as Botox, skin booster injections, mesotherapy, or laser systems. Combined protocols provide comprehensive skin rejuvenation and improved treatment outcomes.
12Is PB Serum Safe? Is It FDA or Ministry of Health Approved?↓
At our clinic, PB Serum is performed exclusively with CE- and FDA-approved, high-quality original products and medical devices that fully comply with Ministry of Health standards.
13When Can I Return to Daily Life After PB Serum?↓
Since PB Serum is a minimally invasive or non-invasive procedure, downtime is minimal to none. Most patients can resume their daily activities and social life immediately after the procedure.
14What Are the Advantages of PB Serum Compared to Other Methods?↓
PB Serum offers significant comfort and advantages over traditional methods, as it requires no surgery, leaves no stitches or scarring, can be performed quickly, and delivers natural-looking results.
15Why Should PB Serum Be Performed by Our Expert Dermatology Team?↓
PB Serum is a medical procedure that requires precise anatomical knowledge and expert physician experience. Our expert dermatology team draws on deep expertise in facial anatomy and skin biology to perform every procedure to the safest standards, tailored specifically to you.

Book Your PB Serum Appointment Now

Schedule a personalized, free initial consultation with our expert physicians.

Contact Us on WhatsApp

Clinic Contact & Appointment

Fast Information Line

+90 (532) 324 94 54

Mon - Sat: 09:00 - 19:00
Nişantaşı / Istanbul

Our Expert Physicians

Dermatology Specialists

All aesthetic procedures and skin analyses are planned individually by your physician.

Clinic Contact Details
Dermal Klinik

Hello! Would you like instant information about treatments and appointments?